Robert Borotkanics


Senior Research Fellow






New Zealand Statistical Association



Dr Borotkanics’ interdisciplinary expertise applies a range of biostatistics approaches to a variety of biomedical, clinical, health services research and public health research collaborations.  His current research collaborations include cancer (breast, prostate, liver), toxicology (chemical and pharmaceutical safety, alternatives to animal testing) and biomarkers (prostate).  He is the lead statistician on a number clinical trials (diabetes, orthopaedics, child health), including multiple international trials in the United States, Australia and the European Union.

He has served in numerous capacities over his career.  Dr. Borotkanics is actively involved in toxicology policy.  He was in the civil service at the US Agency for Healthcare Research and Quality (AHRQ).  He served as a government project officer on a US Institute of Medicine report, “Patient Safety: Achieving a New Standard for Care.”  Dr. Borotkanics is a former Guest Researcher at the US National Institutes of Health, within the National Institutes of Health’s National Institute on Alcohol Abuse and Alcoholism.  He was also a US National Institutes of Health’s of Informatics Research Fellow.

  • DrPH, Johns Hopkins Bloomberg School of Public Health 2014
  • MS, Johns Hopkins School of Medicne 2010
  • MPH, Johns Hopkins Bloomberg School of Public Health 2007
  • Director’s Award for Merit, Agency for Healthcare Research and Quality, US Department of Health and Human Services, 2010
  • Secretary’s Award for Distinguished Service, US Department of Health and Human Services 2003

Research Areas

  • Discriminant analysis
  • Multi-variate. repeated measures with mixed models

  • Environmental Health Sciences
  • Toxicology
  • Alternatives to Animal Testing
  • Risk Assessment (Chemicals and Drug Products)
  • Cancer
  • Clinical Trials
  • Health Services (Safety and Quality)
Doctoral candidates
  • Individuals interested in doctoral training (PhD or Doctor of Health Sciences) are encouraged.  Current doctoral trainees are involved in a range of topics, with strong quantitative emphasis.



Selected publications, most recent five years:

  1. Wormgoor SG, Dalleck L, Zinn C, Borotkanics R, Harris N. High-intensity Interval Training is Equivalent to Moderate-intensity Continuous Training for Short-and Medium-term Outcomes of Macro-and Microvascular Complication Markers in Men with Type 2 Diabetes. Frontiers in endocrinology. 2018;9:475.
  2. Rice D, Kluger M, McNair P, Lewis G, Somogyi A, Borotkanics R, Barratt DT, Walker M. Persistent postoperative pain after total knee arthroplasty: a prospective cohort study of potential risk factors. British Journal of Anaesthesia. 2018;121(4):804-12.Lam TC, Borotkanics R, Hsieh F, Salinas J, Boyages J. Immediate two-stage prosthetic breast reconstruction failure: radiation is not the only culprit. Plastic and reconstructive surgery. 2018;141(6):1315-24.
  3. Lam TC, Borotkanics R, Hseih F, Salinas J, Boyages J. Immediate two-stage prosthetic breast reconstruction failure: radiation is not the only culprit. Plastic and Reconstructive Surgery. 2018;141(6):1315-24.
  4. Taylor L, Kerse N, Klenk J, Borotkanics R, Maddison R. Exergames to Improve the Mobility of Long-Term Care Residents: A Cluster Randomized Controlled Trial. Games for health journal. 2018;7(1):37-42.
  5. Shore ND, Pieczonka CM, Henderson RJ, Bailen JL, Beebe-Dimmer JL, Ruterbusch JJ, Saltzstein DR, Concepcion RS, Borotkanics R, Levin R, Wissmueller S. Evaluation of the MiCheck MIA test performance in differentiating aggressive from non-aggressive prostate cancer: The MiCheck-01 prospective trial. Journal of Clinical Oncology. 2018;36(6_suppl): TPS152-TPS152.
  6. Borotkanics R, Rowe C, Georgiou A, Douglas H, Makeham M, Westbrook J. Changes in the profile of Australians in 77 residential aged care facilities across New South Wales and the Australian Capital Territory. Australian Health Review. 2018;41(6):613-20.
  7. Wang GY, Taylor T, Sumich A, Merien F, Borotkanics R, Wrapson W, Krägeloh C, Siegert RJ. Associations between immunological function and memory recall in healthy adults. Brain and cognition. 2017;119:39-44.
  8. Borotkanics R, Locke P. EPAs methodology to inform TSCA pre-manufacturing notification decision-making: a critical analysis based on chemicals regulated by consent order. International Journal of Risk Assessment and Management. 2017;20(1-3):226-39.
  9. Sen Y, Qian Y, Koelmeyer L, Borotkanics R, Ricketts R, Mackie H, Lam TC, Shon KH, Suami H, Boyages J. Breast Cancer-Related Lymphedema: Differentiating Fat from Fluid Using Magnetic Resonance Imaging Segmentation. Lymphatic research and biology. 2017;16(1):20-7.
  10. McCaughey E, Borotkanics R, Gollee H, Folz R, McLachlan A. Abdominal functional electrical stimulation to improve respiratory function after spinal cord injury: a systematic review and meta-analysis. Spinal cord. 2016;54(9):628.
  11. McCaughey E, Purcell M, McLean A, Fraser M, Bewick A, Borotkanics R, Allan DB. Changing demographics of spinal cord injury over a 20-year period: a longitudinal population-based study in Scotland. Spinal Cord. 2016;54(4):270.
  12. Borotkanics R, Trush M, Locke P. Analysis of ToxCast Data—In Vitro and Physiochemical Properties—In the Accurate Classification of Chemicals That Induce Hepatocarcinogenesis In Vivo. Applied In Vitro Toxicology. 2015;1(4):262-75.
  13. Borotkanics R, Lehmann H. Network motifs that recur across species, including gene regulatory and protein–protein interaction networks. Archives of toxicology. 2015;89(4):489-99.
  14. Rubin MA, Jones M, Leecaster M, Khader K, Ray W, Huttner A, Huttner B, Toth D, Sablay T, Borotkanics R, Gerding DN, Samore MH. A simulation-based assessment of strategies to control Clostridium difficile transmission and infection. PLoS One. 2013;8(11):e80671.